Validitas dan Reliabilitas Instrumen Determinan Kepatuhan Minum Obat pada Pasien Lupus Eritematosus Sistemik

  • Shiane Hanako Sheba
Keywords: adherence determinant, Lupus, reliable instrument, valid instrument

Abstract

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease with
unknown etiology so the patient needs long-term treatment to control the
illness. It could impact physical and economic burden due to serious side
effects and high cost treatment that affect drug adherence. The determinants
of drug adherence vary by location due to social, political and cultural
differences. The aim of this study is to obtain a valid and reliable insrument
of drug adherence determinant for SLE patients.
Quantitative research was conducted on 30 SLE patients at Rheumatology
clinic of Dr. Hasan Sadikin Hospital Bandung with consecutive sampling
technique. Data was analyzed by Rasch model.
The validity of 103 instrument item shows: 83 items are fit statistic; all items
are unidimensional and no inter-items conflict; differences of 4 points scale
are understood by the respondent. Reliability shows: items reliability and
strata separation are excellent; responden reliability and strata separation
are good; Cronbach's Alpha is excellent (0.88).
The result of this study is a valid and reliable instrumen of drug adherence
determinants for SLE patient, representing 51 constructs and 13 categories:
individual characteristics, memory, knowledge, experimentation,
consumption management, disease characteristics, drug characteristics,
costs, hospital policies, access to hospitals, enabler agents, characteristics
of health proffesional and social support.

References

Tutuncu ZN, Kalunian KC. The Definition and clasification of systemic lupus erythematosus. In: Wallace DJ, Hahn BH, editors. Duboi’s lupus erythematosus. 7th ed. Philadelphia. Lippincott William & Wilkins; 2007:16-19.
de Achaval S, Suarez Almazor ME. Treatment adherence to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis and Systemic Lupus Erythematosus. Int J Clin Rheumtol. 2010 June 1;(3): 313–326.
Kamen DL. Adjunctive and preventive measure. Dalam: Wallace DJ, Hahn BH, editor. Dubois, Lupus Erythematosus and related syndrome. Edisi ke-8. Philadelphia:Elsevier Saunders; 2013. hlm. 633-639.
Bugni MV, Ozaki SS, Okamoto KYK. Factors associated with adherence to treatment in children and adolescents with chronic rheumatic diseases. J Pediatr (Rio J). 2012;88(6):483-8.
Abdul-Sattar AB, Abou El Magd SA.Determinants of medication non-adherence in Egyptian patients with systemic lupus erythematosus: Sharkia Governorate.Rheumatol Int. (abstract) 2015; 35 (6): 1045-51.
Julian LJ, Yoolin E, Yazdany J, Panopalis P, Trupin L, Criswell LA, dkk. Depression, medication adherence and service utilization in Systemic lupus erythematosus. Arthritis Rheum. 2009;62(2): 240-246. .
Feldman CH, Yazdany J, Guan H. Medication nonadherence is associated with increased subsequent acute care utilization among medicaid beneficiaries with Systemic Lupus Erythematosus. Arthritis Care & Research. Vol. 67, No. 12, December 2015, pp 1712–1721.
Kang SC, Hwang SJ, Chang YS, Chou CT,Tsai CY. Characteristics of comorbidities and costs among patients who died from Systemic Lupus Erythematosus in Taiwan. Arch Med Sci. 2012; 8(4): 690-696.
Horne R, Weinman J, Barber N, et al. Concordance, adherence and compliance in medicine taking: Report for the National Co-ordinating Centre for NHS Service Delivery and Organisation R & D (NCCSDO). London. 2005. hlm. 48-53.
Lisseanu MG, Greisinger A, Richardson M, et al. Determinants of treatment adherence in ethnically diverse, economically disadvantaged patients with rheumatic disease. J Rheumatol. 2005 May;32(5)[diunduh 1 februari 2016]:913-9. tersedia dari www.ncbi.nlm.nih.gov. Abstrak.
Gonzalez G, Richardson M, Lisseanu MGP, et al. Treatment adherence in patients with rheumatoid arthritis and systemic lupus erythematosus. Rheumatol. 2008 Jul [diunduh 2 Februari 2017];27(7):883-9. Tersedia dari www.ncbi.nlm.nih.gov. Abstrak
Sheba SH, Djuhaeni H, Setiabudiawan B, Sunjaya DK, Mutyara K, Rinawan F. (Maret 2018). Kepatuhan minum obat pada pasien Lupus Eritematosus Sistemik di RSUP Dr. Hasan Sadikin Bandung. Majalah Kedokteran Bandung, 21-28.
Linacre JM. Sample Size and Item Calibration Stability. Rasch Measurement Transactions1994 [diunduh 16 Mei 2016]; 7:4: 328. Tersedia dari www.researchgate.net.
Sumintono B, Widhiarso W. Aplikasi model Rasch untuk penelitian ilmu-ilmu sosial. Edisi revisi; 2015. Trim Komunikata Publishing House. Cimahi
Ward MM. Socioeconomic and Disability Aspects. Dalam: Wallace DJ, Hahn BH, editor. Dubois, Lupus Erythematosus and related syndrome. Edisi ke-8. Philadelphia:Elsevier Saunders; 2013. hlm. 653-658
Published
2018-07-01
How to Cite
1.
Sheba S. Validitas dan Reliabilitas Instrumen Determinan Kepatuhan Minum Obat pada Pasien Lupus Eritematosus Sistemik. Jutek [Internet]. 1Jul.2018 [cited 24Jun.2021];1(1):25-8. Available from: https://jurnal.politeknikalislam.ac.id/index.php/jutek/article/view/21